【pre-PCC】A Potential Best-in-Class CDK2 Inhibitor with Better Selectivity, Better Efficacy and Superior PK【Product for Licensing】

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Project ID:DT-202500410-038

Product Brief Summary

  • Product Name: A Potential Best-in-Class CDK2 Inhibitor with Better Selectivity, Better Efficacy and Superior PK
  • Target: CDK2
  • Modality: Small Molecule
  • Therapeutic Area: Solid Tumor
  • Current Stage: Pre-PCC
  • Rights Available: China/Global Right
  • Collaboration Mode: License out / co-development

More highlights

  • Could solve CDK4/6 resistance by controlling cyclin E-CDK2 activity
  • DTC-038 owns better selectivity, better PD activity and superior PK
  • DTC-038 owns better AUC and lower clearance than PF-07104091
  • Higher drug concentration than PF-07104091 in Breast and Brain
  • Currently at pre-PCC stage

Contact us:

For any questions, please contact DrugTimes BD Team at BD@drugtimes.cn, please include Project ID in the subject. Many thanks!

 

发布者:qi.yang,转载请首先联系contact@drugtimes.cn获得授权

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